Second School IBSS’08 

International System Biology School 

November 3th - 8th, 2008

Tangier - Morocco

MONDAY 3

8:00 - 9:30       School Registration 

Formal approaches to model gene regulatory networks.

Gilles Bernot, University of Nice, France

     9:00-11:00      The modeling frame work of René Thomas

    11:00-11:30      Coffee Break                                   

    11:30-13:00     Formal definitions and examples

    13:00-15:00      Lunch

     15:00-16:30    Temporal logics and model checking

    16:30-17:00     Coffee Break                              

    17:00-18:30     Consistency proofs and in vivo experiments

  18:30- 20:00    Welcom session

 TUESDAY 4

Positive and negative circuits in discrete models of gene networks

Adrien Richard, University of Nice, France

      9:30-10:45     Tutorial: SMBioNet (Selection of Model of Biological Network)

    10:45-11:00     Coffee Break        

    11:00-13:00    Discrete networks and discrete Jacobian matrix

    13:00-15:00     Lunch

    15:00-16:30    Positive circuits and multistationarity          

    16:30-17:00     Coffee Break

    17:00-18:30    Negative circuits and sustained oscillations 

    18:30-19:30     Poster Session

 WEDNESDAY 5

Ontologies & immunoinformatique

Marie-Paule Lefranc, University Montpellier 2,  France

     9:00 - 11:00   IMGT-ONTOLOGY: a must for integrative immunogenetics and immunoinformatics

    11:00-11:30    Coffee Break

    11:30-13:00   Sequence analysis :  IMGT/V-QUEST and IMGT/JunctionAnalysis

    13:00-15:00    Lunch

    15:00-16:30   Tutorial :  IMGT®, the Informatics Framework in immunoinformatics

      Sequence analysis - Tools: IMGT/V-QUEST and IMGT/JunctionAnalysis  

    16:30-17:00    Coffee Break                                      

     17:00-18:30    Tutorial :  IMGT®, the Informatics Framework in immunoinformatics

      Structure analysis - Database: IMGT/3Dstructure-DB

                  Tools: IMGT/DomainGapAlign and IMGT/Collier-de-Perle

    18:30-19:30    Round Table Discussion

      M. Fehmi, Genomics Plateform in Morocco, CNRST, Morocco

    20:00            Social Dinner

THURSDAY 6

9:00-1O:00    Ceremony of the anniversary of " La Marche Verte"

Theories and Modelling of metabolic network.

Jean-Pierre MAZAT, University of Bordeaux, France

    10:30-12:00    The basis of enzymatic kinetics

    12:00-13:30   Metabolic network through the Stoichiometry Matrix

    13:30-15:00    Lunch

    15:00-16:30   Metabolic network : the concept of  elementary modes

    16:30-17:00    Coffee Break

    17:00-18:30    The Metabolic Control Theory
    18:30– 20:00   Poster session

 FRIDAY 7

Data mining in Gene Expression Data Analysis

Martine Collard, University of  Nice-Sophia Antipolis, France

  9:00-11:00     Data Clustering: Concepts and Techniques

    11:00-11:30     Coffee Break

    11:30-13:00    Bi-clustering and Co-clustering approaches

    13:00-15:00     Lunch

     15:00-16:00    BioConductor tools for Gene Expression Clustering

     16:00-16:30    Coffee Break                                                           

     16:30-18:30     BioConductor tools for Gene Expression Clustering

     18:30–20:00    Practical : BioConductor tools

 SATURDAY 8

 9:00 - 11:00    Machine learning methods for high-dimensional and structured data,  

       Lyhyaoui  Abdelouahid, ENSA of Tangier, Morocco 

   11:00-11:30      Coffee Break

    11:30-13:00     Software demonstration: Multi-SOM

    A novel clustering approach for gene expression analysis 

   13:00-15:00       Lunch

    14:00-16:00    Complexes of proteins of genetics regulatory network

   Amal  Maurady, SMBI, Tangier, Morocco  

   16:00-18:30    Historical visit of Tangier and Departure